研究業績リスト

[荻野 教授]

原著論文・総説(英文)

1. Ochi, H., Kawaguchi, A., Tanouchi, M., Suzuki, N., Kumada, T., Iwata, Y. and *Ogino, H.
Co-accumulation of cis-regulatory and coding mutations during the pseudogenization of the Xenopus laevis homoeologs L and six6.S.
Dev. Biol., 427: 84-92 (2017) (doi: 10.1016/j.ydbio.2017.05.004).

2. Ochi, H., Suzuki, N., Kawaguchi, A. and Ogino, H.
Asymmetrically reduced expression of hand1 homeologs involving a single nucleotide substitution in a cis-regulatory element.
Biol., 425: 152-160 (2017) (doi: 10.1016/j.ydbio.2017.03.021).

3. Watanabe, M., Yasuoka, Y., Mawaribuchi, S., Kuretani, A., Ito, M., Kondo, M., Ochi, H., Ogino, H., Fukui, A., Taira, M. and *Kinoshita, T.
Conservatism and variability of gene expression profiles among homeologous transcription factors in Xenopus laevis.
Biol., 426: 301-324 (2017) (doi: 10.1016/j.ydbio.2016.09.017).

4. Session, M. A., Uno, Y., Kwon, T., Chapman, J. A., Toyoda, A., Takahashi, S., Fukui, A., Hikosaka, A., Suzuki, A., Kondo, M., van Heeringen, S. J., Quigley, I., Heinz, S., Ogino, H., Ochi, H., Hellsten, U., Lyons, J. B., Simakov, O., Putnam N., Stites, J., Kuroki, Y., Tanaka, T., Michiue, T., Watanabe, M., Bogdanovic, O., Lister, R., Georgiou, G., Paranjpe, S. S., van Kruijsbergen, I., Shengquiang, S., Carlson, J., Kinoshita, T., Ohta, Y., Mawaribuchi, S., Jenkins, J., Grimwood, J., Schmutz, J., Mitros, T., Mozaffari, S. V., Suzuki, Y., Haramoto, Y., Yamamoto, T. S., Takagi, C., Heald, R., Miller, K., Haudenschild, C., Kitzman, J., Nakayama, T., Izutsu, Y., Robert, J., Fortriede, J., Burns, K., Lotay, V., Karimi, K., Yasuoka, Y., Dichmann, D. S., Flajnik, M. F., Houston, D. W., Shendure, J., DuPasquier, L., Vize, P. D., Zorn, A. M., Ito, M., Marcotte, E., Wallingford, J. B., Ito, Y., Asashima, M., Uneo, N., Matsuda, Y., Veenstra, G. J. C., Fujiyama, A., *Harland, R. M., *Taira, M., *Rokhsar, D. S.
Genome evolution in the allotetraploid frog Xenopus laevis.
Nature
, 538: 336-343 (2016) (doi: 10.1038/nature19840).

5. Aoki, H., Ogino, H., Tomita, H., Hara, A. and *Kunisada, T.
Disruption of Rest Leads to the Early Onset of Cataracts with the Aberrant Terminal Differentiation of Lens Fiber Cells.
PLoS One. 11: e0163042 (2016) (doi: 10.1371/journal.pone.0163042)

6. Suzuki, N., Hirano, K., Ogino, H. and *Ochi, H.
Identification of distal enhancers for Six2 expression in pronephros.
J. Dev. Biol. 59: 241-246 (2015) (doi: 10.1387/ijdb.140263ho).

7. Hayashi, S., Kawaguchi, A., Uchiyama, I., Kawasumi-Kita, A., Kobayashi, T., Nishide, H., Tsutsumi, R., Tsuru, K., Inoue, T., Ogino, H., Agata, K., Tamura, K. and *Yokoyama, H.
Epigenetic modification maintains intrinsic limb-cell identity in Xenopus limb bud regeneration.
Biol., 406: 271-282 (2015) (doi:10.1016/j.ydbio.2015.08.013).

8. Hayashi, S., Ochi, H., Ogino, H., Kawasumi, A., Kamei, Y., Tamura, K. and *Yokoyama, H.
Transcriptional regulators in the Hippo signaling pathway control organ growth in Xenopus tadpole tail
Dev. Biol.
396: 31-41 (2014) (doi:10.1016/j.ydbio.2014.09.018)

9. Omori, A., Miyagawa, S., Ogino, Y., Harada, M., Ishii, K., Sugimura, Y., Ogino, H., Nakagata, N. and *Yamada, G.
Essential roles of epithelial bone morphogenetic protein signaling during prostatic development.
Endocrinology 155: 2534-2544 (2014) (doi: 10.1210/en.2013-2054).

10. Yajima, H., Suzuki, M., Ochi, H., Ikeda, K., Sato, S., Yamamura, K. I., Ogino, H., Ueno, N. and *Kawakami, K.
Six1 is a key regulator of the developmental and evolutionary architecture of sensory neurons in craniates.
BMC Biol. 12: 40 (2014) (doi:10.1186/1741-7007-12-40).

11. *Ochi, H., Kawaguchi, A. and Ogino, H.
Differential use of paralogous genes via evolution of cis-regulatory elements for divergent expression specificities.
New Principles in Developmental Processes, Kondoh, H. and Kuroiwa, A. (ed), Chapter 21 (p279-290), Springer, ISBN 978-4-431-54634-4 (2014).

12. Nabeshima, A., Nishibayashi, C., Ueda, Y., Ogino, H. and *Araki, M.
Loss of cell-extracellular matrix interaction triggers retinal regeneration accompanied by Rax and Pax6
Genesis 51: 410-419 (2013) (doi: 10.1002/dvg.22378).

13. Ochi, H., Tamai, T., Nagano, H., Kawaguchi, A., Sudou, N. and *Ogino, H.
Evolution of a tissue-specific silencer underlies divergence in the expression of pax2 and pax8
Nature Communications 3: 848 (2012).

14. Kawaguchi, A., Ochi, H., Sudou, N. and *Ogino, H.
Comparative expression analysis of the H3K27 demethylases, JMJD3 and UTX, with the H3K27 methylase, EZH2, in Xenopus.
J. Dev. Biol. 56: 295-300 (2012).

15. Sudou, N., Yamamoto, S., Ogino, H. and *Taira, M.
Dynamic in vivo binding of transcription factors to cis-regulatory modules of cer and gsc in the stepwise formation of the Spemann-Mangold organizer.
Development 139: 1651-1661 (2012).

16. *Ogino, H., Ochi, H., Reza, H. M. and Yasuda, K.
Transcription factors involved in lens development from the preplacodal ectoderm.
Biol. 363: 333-347 (2012).

17. *Ogino, H., Ochi, H., Uchiyama, C., Louie, S. and Grainger, R. M.
Comparative genomics-based identification and analysis of cis-regulatory elements.
Methods in Molecular Biology, Xenopus Protocols, 2nd edition: Post-Genomic Approaches, Chapter 17, Humana press, ISBN-10: 1617799912; ISBN-13: 978-1617799914 (2012).

18. *Yokoyama, Y., Maruoka, T., Ochi, H., Aruga, A., Ohgo, S., Ogino, H. and Tamura, K.
Different requirement for Wnt/β-catenin signaling in limb regeneration of larval and adult
PLoS ONE
6(7): e21721 (2011).

19. Sato, S., Ikeda, K., Shioi, G., Ochi, H., Ogino, H., Yajima, H. and *Kawakami, K.
Conserved expression of mouse Six1 in the pre-placodal region (PPR) and identification of an enhancer for the rostral PPR.
Biol. 344: 158-171 (2010).

20. *Hellsten, U., Harland, R. M., Gilchrist, M. J., Hendrix, D. Jurka, J., Kapitonov, V., Ovcharenko, I., Putnam, N. H., Shu, S., Taher, L., Blitz, I. L., Blumberg, B., Dichmann, D. S., Dubchak, I., Amaya, E., Fletcher, R., Gerhard, D., Goodstein, D., Graves, T., Grigoriev, I. V., Grimwood, J., Kawashima, T., Lindquist, E., Mead, P. E., Mitros, T., Ogino, H., Ohta, Y., Poliakov, A. V., Pollet, N., Robert, J., Salamov, S., Sater, A. K., Schmutz, J., Terry, S., Vize, P. D., Warren, W. C., Wells, D., Wills, A., Zimmerman, L. B., Zorn, A. M., Grainger, R., Grammer, T., Khokha, M. K., Richardson, P. M. and Rokhsar, D. S.
The genome of the western clawed frog Xenopus tropicalis.
Science 328: 633-636 (2010).

21. Kurokawa, D., Ohmura, T., Ogino, H., Takeuchi, M., Inoue, A., Inoue, F., Suda, Y. and *Aizawa, S.
Evolutionary origin of the Otx2 enhancer for its expression in visceral endoderm.
Biol. 342: 110-120 (2010).

22. *Ogino, H. and Ochi, H.
Resources and transgenesis techniques for functional genomics in Xenopus.
Growth Differ. 51: 387-401 (2009).

23. Ogino, H., Fisher, M. and *Grainger, R. M.
Convergence of a head-field selector Otx2 and Notch signaling: a mechanism for lens specification.
Development135: 249-258 (2008).

24. Yokoyama, H., Ogino, H., Stoick-Cooper, C. L., Grainger, R. M. and *Moon, R. T.
Wnt/b-catenin signaling has an essential role in the initiation of limb regeneration.
Biol. 306: 170-178 (2007).

25. Ogino, H., McConnell, W. B. and *Grainger, R. M.
High-throughput transgenesis in Xenopus using I-SceI
Nature Protocol 1: 1703-1710 (2006).

26. Ogino, H., McConnell, W. B. and *Grainger, R. M.
Highly efficient transgenesis in Xenopus tropicalis using I-SceI
Mech. Dev. 123: 103-113 (2006).

27. Ochi, H., Sakagami, K., Ishii, A., Morita, N., Nishiuchi, M., Ogino, H. and *Yasuda, K.
Temporal expression of L-Maf and RaxL in developing chicken retina are arranged into mosaic pattern.
Gene Expr. Patterns 4: 489-494 (2004).

28. Peng, J., Riggs, B. L., Ogino, H. and *Blumberg, B.
Construction of a set of full-length enriched cDNA libraries as genomics tools for Xenopus tropicalis
Current Genomics 4: 635-644 (2003).

29. Ochi, H., Ogino, H., Kageyama, Y. and *Yasuda, K.
The stability of the lens-specific Maf protein is regulated by FGF/ERK signaling in lens fiber differentiation.
Biol. Chem. 278: 537-544 (2003).

30. Hirsch, N., Zimmerman, L. B., Gray, J., Chae, J., Curran, K. L., Fisher, M., Ogino, H. and *Grainger, R. M.
Xenopus tropicalis transgenic lines and their use in the study of embryonic induction.
Dyn. 225: 522-535 (2002).

31. Reza, H. M., Ogino, H. and *Yasuda, K.
L-Maf, a downstream target of Pax6, is essential for chick lens development.
Dev. 116: 61-73 (2002).

32. Kajihara, M., Kawauchi, S., Kobayashi, M., Ogino, H., Takahashi, S. and *Yasuda, K.
Isolation, characterization, and expression analysis of zebrafish large Mafs.
Biochem. 129: 139-146 (2001).

33. *Ogino, H. and Yasuda, K.
Sequential activation of transcription factors in lens induction.
Growth Differ. 42: 437-448 (2000).

34. Kawauchi, S., Takahashi, S., Nakajima, O., Ogino, H., Morita, M., Nishizawa, M., Yasuda, K. and *Yamamoto, M.
Regulation of lens fiber cell differentiation by transcription factor c-Maf.
Biol. Chem. 274: 19254-19260 (1999).

35. Ogino, H. and *Yasuda, K.
Induction of lens differentiation by activation of a bZIP transcription factor, L-Maf.
Science 280:115-118 (1998).

36. Duncan, M. K., Li, X., Ogino, H., Yasuda, K. and *Piatigorsky, J.
Developmental regulation of the chicken bB1-crystallin promoter in transgenic mice.
Dev. 57:79-89 (1996).

 

日本語総説

1. *荻野 肇
全ゲノム重複に伴うシス調節配列の進化.
生体の科学 66: 256-260 (2015)

2. *荻野 肇,Hasan Mahmud Reza,阪上起世,安田國雄
転写因子の異所的発現と機能阻害 眼形成の分子機構へのアプローチ.
細胞工学 18: 1556-1561(1999).

3. *安田國雄,荻野 肇
L-Mafによる水晶体分化の誘導.
実験医学 16: 1571-1573 (1998).

4. *荻野 肇,安田國雄
クリスタリン遺伝子発現制御とmafファミリー.
蛋白質核酸酵素 41: 1050-1057 (1996).

5. *荻野 肇,安田國雄
水晶体分化とmaf遺伝子ファミリー.
細胞工学 14: 774-780 (1995).

6. *安田國雄,松尾勲,仁田正弘,荻野 肇
クリスタリン遺伝子の組織特異的な発現にかかわる転写制御因子.
実験医学 11: 992-998 (1993) .

7. *安田國雄,松尾勲,荻野 肇
aA-クリスタリン遺伝子の転写制御.
実験医学 10: 1656-1662 (1992).

 

著書

1. *荻野 肇
「1枚の写真館—研究は手を替え品を替え」
細胞工学(秀潤社)、34 (4), 343 (2015).

2. *荻野 肇
「ルシフェラーゼアッセイ」
別冊実験医学 ザプロトコールシリーズ non-RI実験の最新プロトコール(羊土社), 145-150 (1999).

3.  *荻野 肇
「mafファミリー」
Bioscience新用語ライブラリー 転写因子 第2版(羊土社), 192-193 (1999).

4. *荻野 肇,安田國雄
「c-maf」
BioScience 用語ライブラリー (羊土社), 198-199 (1995).

5. *安田國雄,荻野 肇
「サウスウェスタン法」
バイオマニュアルシリーズ5 転写因子研究法(羊土社), 177-188 (1993).

 

 

[ 柏木昭彦 客員教授]

原著論文・総説

1.Goto-Inoue, N., Sato, T., Mizuki, M., Kashiwagi, A., Kashiwagi, K., Sugiura, Y., Sugiyama, E., Suematsu, M. and Mori, T.
Utilizing mass spectrometry imaging to map the thyroid hormones triiodothyronine and thyroxine in Xenopus tropicalis tadpoles.
Anal. Bioanal. Chem. 410:1333-1340 (2018) (doi: 10.1007/s00216-017-0775-y)

2. Mori, J., Sanoh, S., Kashiwagi, K., Hanada, H., Shigeta, M., Suzuki, K.T., Yamamoto, T., Kotake, Y., Sugihara, K., Kitamura, S., Kashiwagi, A. and Ohta, S.
Developmental changes in drug-metabolizing enzyme expression during metamorphosis of Xenopus tropicalis.
J. Toxicol. Sci. 42(5):605-613(2017) ( doi: 10.2131/jts.42.605)

3. Mori, T., Yanagisawa, Y., Kitani,Y., Yamamoto,G., Goto-Inoue1,N. Kimura,T., Kashiwagi, K. and Kashiwagi, A.
The constant threat from a non-native predator increases tail muscle and fast-start swimming performance in Xenopus tadpoles
Biology Open 6, 1726-1733 (2017) (doi:10.1242/bio.029926)

4. Kashiwagi, K., Kashiwagi, A. and Iwasaka M.
Effect of magnetic fields on the green color formation in frog skin. Magneto-Elastic and Magneto-Optic Materials.
AIP Advances 7, 056426 (2017) ( doi: http://dx.doi.org/10.1063/1.4976958)

5. Goto-Inoue,N., Kashiwagi,A., Kashiwagi,K. and Tsukasa Mori.
Metabolomic approach for identifying and visualizing molecular tissue markers in tadpoles of Xenopus tropicalis by mass spectrometry imaging.
Biology Open 5,1252-1259 (2016) (doi:10.1242/bio.O19646)

6. Shigeta, M., Sakane,Y., Iida, M., Suzuki, M., Kashiwagi, K., Kashiwagi, A., Fujii, S., Yamamoto, T. and Suzuki, K.T.
A streamlined workflow for rapid and efficient gene disruption by CRISPR-Cas9 in Xenopus tropicalis founders.
Genes Cells. (2016)( doi: 10.1111/gtc.12379.)

7. Nakade, S., Sakuma, T., Sakane, Y., Hara, Y., Kurabayashi, A., Kashiwagi, K., Kashiwagi,A.,
Yamamoto, T. and Obara, M.
Homeolog-specific targeted mutagenesis in Xenopus laevis using TALENs.
In Vitro Cellular & Developmental Biology─Animal, 51: 879-884. (2016)

8. Igawa,T., Watanabe,A., Suzuki, A., Kashiwagi, A., Kashiwagi,K., Noble,A., Guille,M., Simpson, D.E., Horb, M.E., Fujii, T. and Sumida, M.
Inbreeding ratio and genetic relationships among strains of the Western Clawed Frog, Xenopus tropicalis.
PLoS ONE, 10(7): e0133963 (2015)

9. Hanada, H., Kashiwagi, K., Suzuki, K.T., Yamamoto, T. and Kashiwagi, A.
Suppression of anuran metamorphosis by synthetic chemicals.
Genetic Diversity, Neural Development and Environmental Influences. p.73-88. (Nova, Sweden). (2014)

10. Hanada , H., Kobuchi, H., Yamamoto, M., Kashiwagi, K., Katsu, K., Utsumi, T., Kashiwagi, A., Sasaki, J., Inoue, M. and Utsumi, K.
Acetyl-L-carnitine suppresses thyroid hormone-induced and spontaneous anuran tadpole tail shortening.
Hereditas, 150: 1-9. (2013)

11. Suzuki, K.T., Isoyama, Y., Kashiwagi, K., Sakuma, T., Ochiai, H., Sakamoto, N., Furuno, N., Kashiwagi, A. and Yamamoto, T.
High efficiency TALENs enable F0 functional analysis by targeted gene disruption in Xenopus laevis embryos.
Biology Open, BIO_2013_3855. doi: 10. 1242/bio.20133855: 1-5. (2013)

12. Sakane,Y., Sakuma,T., Kashiwagi, K., Kashiwagi, A., Yamamoto, T. and Suzuki, K.T.
Targeted mutagenesis of multiple and paralogous genes in Xenopus laevis using two pairs of
transcription activator-like effector nucleases.
Dev. Growth Diff., 2014, 108-114. (2013)

13. Yanagisawa, M., Kashiwagi, K., Hanada, H., Shinkai, T., Yoshitome, S., Kubo, H., Itai, M.,
Fujii, H., Yamashita, M., Kashiwagi, A., Watanabe, M. and Furuno, N.
Analysis of the head-defects caused by hypergravity in early Xenopus embryos.
Biol. Sci. Space, 26: 1-6. (2012)

14. Yanagisawa, M., Kashiwagi, K., Hanada, H., Shinkai, T., Yoshitome, S., Kubo, H., Sakai, M.,
Fujii, H., Yamashita, M., Kashiwagi, A., Watanabe, M. and Furuno, N.
Hypergravity specifically affects anterior head formation in early Xenopus embryos.
Biol. Sci. Space., 26: 47-52. (2012)

15. Yanagisawa, M., Furuno, N., Watanabe, M., Kashiwagi, K., Hanada, H., Shinkai, T., Yoshitome,
S., Kubo, H., Sakai, M., Fujii, H., Suzuki, K., Yamashita, M. and Kashiwagi, A.
Hypergravity specifically effects head formation in the Xenopus embryos raseid under hypergravity
condition.
Space Utili. Res., 28:172-175. (2012)

16. Fujiwara, Y., Kashiwagi, K., Nakagawa, M., Shinkai, T., Yanagisawa, M., Furuno, N., Hanada,
H., Suzuki, K., Katsu, K., Yamashita, M., Yamamoto, T., Tanimoto, Y. and Kashiwagi, A.
Effects of magnetically controllled microgravity and hypergravity environment on amphibian
behavior.
Space Utili. Res., 28:176-179. (2012)

17. Yanagisawa, M., Furuno, N., Watanabe, M., Kashiwagi, K., Hanada, H., Shinkai, T., Yoshitome,
S., Kubo, H., Itai, M., Fujii, H., Suzuki, K. T., Yamashita, M. and Kashiwagi, A.
Molecular analyses of the head-defects in the Xenopus embyos rased under hypergravity conditions.
Space Utili. Res., 27: 198-200. (2011)

18. Furuno, N., Futsuki, D., Kawasaki, T., Shiraga, M.,Tanimoto,Y., Kashiwagi, K., Suzuki,K.T., Yamashita, M.and Kashiwagi, A.
Effect of strong static magnetic fields on the amphibian life cycle – Effect on oocyte maturation of
Silurana tropicalis.
Space Utiliz, Res., 26: 228-231. (2010)

19. Kashiwagi, K., Fujiwara, Y., Sakao, S., Furuno, N., Yanagisawa, M., Hanada, H., Tanimoto, Y.,
Yamashita, M., Watanabe, M., Shinkai, T., Yoshitome, S., Kubo, H., Sakai, M., Fujii, H., Naitoh,
T., Suzuki, K.T. and Kashiwagi, A.
Effect of strong static magnetic fields on the amphibian life cycle – morphological and molecular
biological analyses of early development.
Space Utiliz, Res., 26 : 232-235. (2010)

20. Kashiwagi, K., Kashiwagi, A., Kurabayashi, A., Hanada, H., Nakajima, K., Okada, M., Takase, M. and Yaoita, Y.
Xenopus tropicalis: An ideal experimental animal in amphibia.
Exp. Anim., 59(4) 395-405. (2010)

21. Suzuki, K.T., Kashiwagi, K., Ujihara, M., Marukane, T., Tazaki, A., Watanabe, K., Mizuno, N., Ueda, Y., Kondoh, H., Kashiwagi, A. and Mochii, M.
Characterization of a novel type I keratin gene and generation of transgenic lines with fluorescent reporter genes driven by its promoter/enhancer in Xenopus laevis .
Dev. Dyn., 239: 3172-3181.(2010)

22. Furuno, N., Futsuki, D., Kawasaki T., Shiraga, M., Tanimoto, Y., Kashiwagi, K., Suzuki, K., Yamashita, M. and Kashiwagi, A.
Effect of strong static magnetic fields on amphibian life cycle──Effect on oocyte maturation in Xenopus topicalis─
Space Utiliz. Res., 26: 228-231. (2010)

23. Oka, T., Miyahara, M.,Yamamoto, J., Mitui, N., Fujii, T., Tooi, O., Kashiwagi, K., Takase,M., Kashiwagi, A. and Iguchi, T.
Application of metamorphosis assay to a native Japanese amphibian species, Rana rugosa, for assessing effects of thyroid system affecting chemicals.
Ecotoxicol. Environ. Saf., 64: 281-287. (2009)

24. Kashiwagi, K., Furuno, N., Hanada, H., Kitamura, S., Utsumi, K., Taniguchi,K., Ohta, S., Sugihara, K., Suzuki, K.T. and Kashiwagi, A.
Review. Disruption of thyroid hormone function by environmental pollutants.
J. Health Sci., 55: 147-160. (2009)

25. Suzuki, K.,T., Machiyama, F., Nishino, S., Watanabe, Y., Kashiwagi, K., Kashiwagi, A. and Yoshizato, K.
Molecular features of thyroid hormone-regulated skin remodeling in Xenopus laevis during metamorphosis.
Dev. Growth Differ., 51: 411-427. (2009)

26. Watanabe, M., Yanagisawa, M., Furuno, N., Kashiwagi, K., Shinkai, T., Hanada, H., Yoshitome, S., Kubo, H., Itai, M., Fujii, H., Yamashita, M. and Kashiwagi, A.
Analysis of Head-Defects in Xenopus Embryos Raised under Hypergravity Condition.
Space Utiliz. Res., 25: 155-158. (2009)

27. Kashiwagi,A., Utsumi,K., Kashiwagi, K., Ohta, S., Sugihara, K., Hanada, H. and Kitamura, S.
Minireview. Effects of endocrine disrupting chemicals on amphibian metamorphosis and mitochondrial membrane permeability transition.
J. Health Sci., 54: 273-280.(2008)

28. Kashiwagi, K., Hanada, H., Yamamoto, T., Goto, Y., Furuno, N., Kitamura,S., Ohta,S., Sugihara, K., Taniguchi, K, Tooi, O., Suzuki, K.T., Yoshizato,K. and Kashiwagi, A.
2-Hydroxy-4-methoxybenzophenone(HMB) and 2,4,4’-trihydroxybenzophenone (THB) suppress amphibian metamorphosis.
Progr. Safe. Technol., 7: 970-976. (2008)

29. Oka, T., Tooi, O., Mitsui, N., Miyahara, M., Ohnishi, Y., Takase, M., Kashiwagi, A., Shinkai, T., Santo, N. and Iguchi, T.
Effect of atrazine on metamorphosis and sexual differentiation in Xenopus laevis.
Aquatic Toxicol., 87: 215-226. (2008)

30. Nishimura, M., Okimura, Y., Fujita,H., Kashiwagi, A., Yano, H., Lee, J., Suzaki, E., Inoue, M., Utsumi,K. and Sasaki, J.
Mechanism of 3-nitropropionic acid-induced membrane permeability transition of
isolated mitochondria and its suppression by L-carnitine.
Cell Biochem. Funct., 26: 881-891. (2008)

31. Shinkai, T., Kashiwagi, A., Kashiwagi, K., Furuno, N., Hanada, H., Kubo, H., Yoshitome, S., Watanabe, M., Fujii, H., Itai, M. and Yamashita, M.
Effects of Thyroxine on the Mulfunction of Pituitary-Thyroid Axis by Exposing Hypergravity in the Tropical clawed frog Xenopus tropicalis.
Space Utiliz. Res., 24: 242-245. (2008) .

32. Furuno, N., Tazawa, I., Kashiwagi, K., Shinkai, T., Yoshitome, S., Watanabe, M., Yamashita, M.
and Kashiwagi, A.
Effects of hypergravity on oocyte maturation in Xenopus laevis.-II.
Space Utliz. Res., 23: 311-313. (2007)

33. Shinkai, T., Matsuda, M., Kashiwagi, A., Kashiwagi, K., Furuno, N., Urano, S., Kubo, H.,
Sakai,M., Fujii, H. and Yamashita, M.
Effects of hypergravity of hypothalamus-Pituitary axis in the frog, Xenopus laevis.
Space Utliz. Res., 23: 314-317. (2007)

35. Kashiwagi, A., Kashiwagi, K., Saito, S., Date-Ito, A., Ichikawa, M., Mori, Y., and Hagino-
Yamagishi, K.
Stable knock-down of vomeronasal receptor genes in transgenic Xenopus tadpoles.
Biochem. Biophys. Res. Commun., 345: 140-147. (2006)

36. Goto, Y., Kitamura, S., Kashiwagi, K., Oofusa, K., Tooi, O., Yoshizato, K., Sato, J., Ohta, S. and
Kashiwagi, A.
Suppression of amphibian Metamorphosis by bisphenol A and related chemical substances.
J. Health Sci., 52: 160-168. (2006)

37. Tazawa, I., Kashiwagi, A., Kashiwagi, K. and Furuno. N.
Effects of hypergravity on oocyte maturation in Xenopus laevis.
Biol. Sci. Space, 19: 242-244. (2006)

38. Tazawa, I., Okumoto, H. and Kashiwagi, A.
Skin pigmentary variants in Rana nigromaculata.
J. Clinic. Biochem. Nutri., 38: 195-203. (2006)

39. Fujita, H., Okimura, Y., Utsumi, T., Kitamura, S., Kuroki, H., Otsuki, T., Kashiwagi, A. and
Utsumi,
4-Hydroxy-3, 5, 3′, 4′-tetrachlorobiphenyl induced membrane permeability transition in isolated rat
liver mitochondria.
J. Clin. Biochem. Nutr., 38: 167-175. (2006)

40. Kawakami, S., Kashiwagi, K., Furuno, N., Yamashita, M. and Kashiwagi , A.
Effects of hypergravity environments on amphibian development, gene expression and apoptosis.
Comp. Biochem. Physiol., part A. 145: 65-72.(2006)

41. Kawakami, S., Kashiwagi, K., Furuno, N., Yamashita, M., Kashiwagi , A. and Tanimoto, Y.
Effects of strong static magnetic fields on amphibian development and gene expression.
Jap. J. Appl. Phys., 45: 6055-6056. (2006)

42. Kawakami,S., Kashiwagi, K., Furuno, N., Kashiwagi, A., Yamashita, M. and Tanimoto,Y.
Influence of hypergravity and high magnetic field on the development and gene
expression of Xenopus laevis.
Jap. J. Appl. Phys., 59: EA62. (2006)

43. Shinkai, T., Kashiwagi, A., Kashiwagi, K., Matsuda, K., Urano, S., Sato, H., Kubo, H., Furuno,
N., Itai, M., Watanabe, M., Yoshitome, S., Fujii, H. and Yamashita, M.
Effects of hypergravity on pituitary-target organs in the frog, Xenopus laevis.
Biol. Sci. Space, 20: 40-43. (2006)

44. Furuno, N.,Tazawa, I., Kashiwagi, K., Kawakami, S., Shinkai, T., Yamashita, M. and Kashiwagi, A.
The effect of hypergravity on bipolar spindle formation on meiosis II in Xenopus oocytes.
Biol. Sci. Space, 20: 92-94. (2006)

45. Furuno N., Tazawa I., Kashiwagi K., Kawakami S., Yoshitom, S., Watanabe M., Yamashita, M.
and Kashiwagi, A.
Effects of hypergravity on oocyte maturation in Xenopus laevis.-I
Space Utiliz. Res., 22: 228-230. (2006).

46. Shinkai, T., Kashiwagi, A., Kashiwagi, K., Furuno, N., Urano, S., Sato, H., Kubo, H.,
Itai, M., Watanabe, M., Yoshitome, S., Fujii, H. and Yamashita, M.
Effects of Hypergravity on Pituitary-target organ axes in the African clawed frog
Xenopus laevis.
Space Utiliz. Res., 22: 231-234. (2006).

47. Mitsui, N., Fujii, T., Miyahara, M., Oka, T., Kashiwagi, A., Kashiwagi, K., Hanada, H.,
Urushitani, H., Santo, N., Tooi, O. and Iguchi, T.
Development of metamorphosis assay Silurana tropicalis for the detection of thyroid
system-disrupting chemicals
Ecotoxicol. Environ. Safety, 64: 281-287. (2006)

48. Matsumura, N., Ishibashi, H., Hirano, M., Nagao, Y., Watanabe, N., Shiratsuchi, H., Kai, T.,
Nishimura, T., Kashiwagi, A. and Arizono, K..
Effects of nonylphenol and triclosan on production of plasma vitellogenin and testosterone in male
South African clawed frogs (Xenopus laevis).
Biol. Pharm. Bull., 28: 1748-1751. (2005)

49. Kashiwagi, K., Shinkai, T., Kajii, E. and Kashiwagi, A.
The effect of reactive oxygen species on amphibian aging.
Comp. Biochem. Physiol. C 140: 197-120. (2005)

50. Kashiwagi, A., Furuno N., Kashiwagi K., Hanada H., Kawakami S., Watanabe M. and Yamashita M.
Effects of gravity on the amphibian life cycle──morphological and molecular biological analyses of early development, morphogenesis and metamorphosis
Space Utiliz. Res., 21: 270-273. (2005)

51. Kitamura, S., Kato, T., Iida, M., Jinno, N., Suzuki, T., Ohta, S., Fujimoto, N., Hanada, H.,
Kashiwagi, K. and Kashiwagi, A.
Anti-thyroid hormonal activity of tetrabromobisphenol A, a flame retardant, and related compounds:
affinity to the mammalian thyroid hormone receptor, and effect on tadpole metamorphosis.
Life Sci., 76: 1589-1601. (2005)

52. Inoue, M., Sato E.F., Nishikawa, M., Hiramoto, K., Kashiwagi, A. and Utsumi, K.
Free radical theory of mitochondria-dependent apoptosis and metamorphosis.
Redox Report, 9: 237-247. (2004)

53. Kondo, Y., and Kashiwagi, A.
Experimentally induced autotetraploidy and allotetraploidy in two pond frogs.
J. Herptol., 38: 128-139. (2004)

54. Miyazawa, T., Yamashita, M., Kashiwagi, A. and Naitoh, T.
Motility of Intestine in the Bombina orientaris tadpole.
Space Utiliz. Res., 20: 49-52. (2004)

55. Kashiwagi, A., Kawakami, S., Hanada, H., Kashiwagi, K. and Gusev, O.
Apoptosis, changes in body morphology and function, and effects of gravity during
amphibian metamorphosis.
Space Utiliz. Res., 20: 57-60. (2004)

56. Kashiwagi, A., Kashiwagi, K., Hanada, H., Kubo, H., Shinkai, T., Fujii, H. and
Yamashita, M.
Apoptosis, changes in body morphology and function, and effects of gravity during
amphibian metamorphosis.
Space Utiliz. Res., 19: 45-48. (2003)

57. Kashiwagi, A., Hanada, H., Kawakami, S., Kubo, H., Shinkai, T., Fujii, H. and Kashiwagi,K.
Effects of high gravity on amphibian development.
Biol. Sci.Space, 17: 215-216. (2003)

58. Hanada H., Katsu K., Kanno T., Sato, E., Kashiwagi, A., Sasaki, J., Inoue,M. and
Utsumi, K.
Cyclosporin A inhibits thyroid hormone-indiced shortening of the tadpole tail through
membrane permeability transition.
Comp. Biochem. Physiol. B Biochem. Mol. Biol., 135: 473-483. (2003)

59. Oofusa, K., Tooi, O., Kashiwagi, A., Kashiwagi, K., Kondo, Y., Obara. M. and Yoshizato, K.
Metal ion-responsive transgenic Xenopus laevis as an environmental monitoring animal.
Environ. Toxicol. Pharmacol., 13: 153-159. (2003)

60. Kashiwagi, A., Kashiwagi, K., Hanada, H., Kubo, H., Shinkai, T., Fujii, H. and
Yamashita, M.
Apoptosis, changes in body morphology and function, and effects of gravity during
amphibian metamorphosis.
Space Utiliz. Res., 18: 109-112. (2002)

61. Oofusa, K., Tooi, O., Kashiwagi, A., Kashiwagi, K., Kondoh, Y., Watanabe, Y., Sawada, T.,
Fujikawa, T. and Yoshizato, K.
Expression of thyroid hormone receptor beta gene assayed by transgenic Xenopus laevis carrying its
promoter sequences.
Mol. Cell. Endocrinol.,181: 97-110. (2001)

62. Kashiwagi A., Kanno T., Arita K., Ishisaka R., Utsumi T., Utsumi K.
Suppression of T3- and fatty acid-induced membrane permeability transition by L-carnitine.
Comp. Biochem. Physiol. B Biochem. Mol. Biol., 130: 411-418. (2001)

63. Kashiwagi, K. and Kashiwagi, A.
Effects of cadmium chloride on amphibians.
Zoological Science, 18(Suppl), 30. (2001)

64. Kashiwagi, A., Kashiwagi, K., Kubo, H., Shinkai, T. and Fujii, H.
Apoptosis, changes in body morphology and function, and effects of gravity during amphibian metamorphosis.-II
Space Utiliz. Res., 17, 84-87 (2001).

65. Kashiwagi A., Hanada H., Yabuki M., Utsumi K.
Reactive oxygen species and the mechanism for tail apoptosis in Rana rugosa and Rana japonica.
Recent Res. Devel. Comparative Biochem, and Pysiol., 1: 51-66. (2000)

66. Kashiwagi, A., Hanada, H and Utsumi, K.
Apoptosis, changes in body morphology and function, and effects of gravity during amphibian metamorphosis.
Space Utiliz. Res., 16: 63-66. (2000)

67. Yamashita, M., Naitoh T., Kashiwagi A. and Wassersug, R. J.
Amphibian larvae and space biology.
Space Utiliz. Res., 16: 76-79. (2000)

68. Kashiwagi A., Hanada H., Yabuki M., Kanno T., Ishisaka R., Sasaki J., Inoue M., Utsumi K.
Thyroxine enhancement and the role of reactive oxygen species in tadpole tail apoptosis.
Free Radic. Biol. Med., 26: 1001-1009. (1999)

69. Yamashita, M., Naitoh, T., Kashiwagi, A., Kondo, Y. and Wassersug, R. J.
Allometry in vestibular responses of anurans.
Adv. Space Res., 23: 2083-2086. (1999)

70. Kashiwagi, A., Kashiwagi, K., Takase, M., Hanada, H., Yamashita, M., Naitoh, T. and
Nakamura, M.
Inhibitor and temperature effect on catalase in the liver of adult diploid and haploid Rana rugosa.
Comp. Biochemi. Physiol., B119: 235-239. (1998)

71. Kashiwagi, A., Hanada, H., Yabuki, M., Kanno, T., Ishisaka, R., Sasaki, J., Inoue, M. and
Utsumi, K.
An investigation into the role of reactive oxygen species in tadpole tail apoptosis by means of
thyroxine enhancement. IBC’s Fifth Annual Conference on Apoptosis,
International Business Communications, 281. (1998)

72. Miura, I., Nakajima, T., Ohtani, H., Kashiwagi, A. and Nakamura, M.
Molecular cloning of cDNA for the isoform of the 14-3-3 protein: homologous sequences in the
3’-untranslated region of frog and human isoforms.
Zool. Sci.,14: 771-775. (1997)

73. Nakamura, M., Kawano,K., Kondo, I.,Kashiwagi, A. and Yamamoto. S.
Stage-development distribution of calreticulin in oocytes of the frog, Rana rugosa.
Zool. Sci.,14: 935-940. (1997)

74. Nakajima, T., Miura,I., Kashiwagi, K. and Nakamura, M.
Molecular cloning and expression of the KIF3A gene in the frog brain and testis.
Zool.Sci.,14: 917-921. (1997)

75. Kashiwagi, A., Hanada, H., Yabuki, M., Kanno, T., Ishisaka, R., Takehara,Y., Sasaki, J., Inoue,
M. and Utsumi, K.
Molecular mechanism for cell death during amphibian metamorphosis―Preparation for adaptation
from aquatic life to terrestrial life. In Medical Tribune Books: Birth of life and strategy for survival
of living organisms (ed. K. Utsumi and M. Inoue). Tokyo:Nippon Axel Springer. (1997)

76. Kashiwagi, A., Kashiwagi, K., Takase, M., Hanada, H. and Nakamura, M.
Comparison of catalase in diploid and haploid Rana rugosa using heat and chemical inactivation techniques.
Comp. Biochem. Physiol., B118, 499-503. (1997)

77. Hanada H., Kashiwagi A., Takehara Y., Kanno T., Yabuki M., Sasaki J., Inoue M., Utsumi K.
Do reactive oxygen species underlie the mechanism of apoptosis in the tadpole tail?
Free Radic. Biol. Med., 23: 294-301. (1997)

78. Miura, I., Ohtani, H., Hanada, H., Ichikawa, Y., Kashiwagi A. and Nakamura, M.
Evidence for two successive pericentric inversions in sex lampbrush chromosomes of Rana rugosa
(Anura: Ranidae).
Chromosoma 106: 178-182. (1997)

79. Kashiwagi, A. and Kashiwagi, K.
Comparison of liver peroxisomal enzyme activity changes during development of diploid and
haploid anurans.
Comp. Biochem. Physiol., B113: 533-536. (1996)

80. Miura, I., Ohtani, H., Kashiwagi, A., Hanada, H. and Nakamura, M.
Structural differences between XX and ZW sex lampbrush chromosomes in Rana rugosa females.
Chromosoma, 105: 237-241. (1996)

81. Kashiwagi, K. and Kashiwagi, A.
Comparison of peroxisomal enzyme activity changes in the tail of diploid and haploid anuran
tadpoles during metamorphosis.
Comp. Biochem. Physiol., B115: 399-403. (1996)

82. Kashiwagi ,A.
Peroxisomal enzyme activity changes in the tail of anuran tadpoles during
metamorphosis.
Comp. Biochem. Physiol., 111B: 483-489. (1995)

83. Kashiwagi , A.
Phylogenetic relationships of the Rana esculenta group clarified by electrophoretic analyses of serum transferrins.
Sci. Rep. Lab. Amphibian Biol. Hiroshima Univ., 13: 241-249. (1994)

84. Kashiwagi , A.
Distribution of transferrin phenotypes in Rana nigromaculata from Japan and Korea.
Sci. Rep. Lab. Amphibian Biol. Hiroshima Univ., 13: 233-239. (1994)

85. Kashiwagi, K. and Kashiwagi, A.
Artificially produced chimeras between haploids and diploids in Japanese anurans.
Sci. Rep. Lab. Amphibian Biol., Hiroshima Univ., 12: 37-54. (1993)

86. Kashiwagi , A.
Studies on alkaline phosphatase activity in amphibians. III. Effects of inhibitor and temperature on
alkaline phosphatases in Japanese amphibians.
Sci. Rep. Lab. Amphibian Biol., Hiroshima Univ., 10: 243-254. (1990)

87. Kashiwagi , A.
Studies on alkaline phosphatase activity in amphibians. II. Changes in alkaline phosphatase activity
during development in Rana catesbeiana.
Sci. Rep. Lab. Amphibian Biol., Hiroshima Univ.,10: 233-241. (1990)

88. Kashiwagi , A.
Studies on alkaline phosphatase activity in amphibians. I. Alkaline phosphatase activity during
development in Rana japonica and Rana nigromaculata.
Sci. Rep. Lab. Amphibian Biol., Hiroshima Univ.,10: 223-231. (1990)

89. Kashiwagi , A.
Phylogenetic relationships of several Japanese frog species as determined by a serological method.
Sci. Rep. Lab. Amphibian Biol., Hiroshima Univ., 8: 95-108. (1986)

90. Kashiwagi , A.
Serum transferrin phenotypes of Rana japonica distributed in western Japan.
Sci. Rep. Lab. Amphibian Biol., Hiroshima Univ., 5: 155-165. (1981)

著書
1.柏木 昭彦、花田 秀樹、柏木啓子、矢吹 宗久、菅野 智子、石坂 瑠美、竹原 良記、佐々
木順造、井上 正康、内海 耕慥.
生命誕生と生物の生存戦略.
日本アクセル・シュプリンガー出版, メディカルトリビューンブックス (1998)

2. 大房 健、戸笈 修、柏木昭彦柏木啓子、近藤育志、吉里勝利.
「トランスジェニックカエルの作製方法」
実験医学18、795-801. (2000)

3. 大房 健、戸笈 修、柏木昭彦柏木啓子、近藤育志、吉里勝利
「トランスジェニックカエルの作製方法」
実験医学別冊 クローズアップ実験法 78-84. (2002)

4. 柏木昭彦.
衰退していくカエルたち.
広大環境 No. 33, 12-15. (2004)

5. 柏木昭彦.
両生類 太田川生物誌 目で見る生物誌――代表的な生物たち、監修:太田川水系生物相学術
調査委員会 発行:国土交通省中国地方整備局太田川河川事務所、pp.403-433. (2005)

6. 柏木昭彦柏木啓子、古野伸明、新海 正.
Biophilia Special 宇宙での生物観察、実験4 カエルを宇宙へ-アフリカツメガエルを用いた宇宙実験
Biophilia 3, 26-31. ( 2007)

7. Kitamura S, Sugihara K, Nakamura K, Kotake Y, Kashiwagi A, and Fujimoto N: Endocrine Disruption in Toxic Response,
General and Aplied Toxicology (Third edition) Vol. 1, Chapter22, pp539-582. (2009

報告書

1. 柏木 昭彦、花田 秀樹、柏木 啓子、吉里 勝利、武石 全慈、倉本 満、小野 勇一、門上 希和夫“カエル細胞に及ぼすトリニトロトルエンの細胞遺伝学的影響” 北九州における外因性内分泌撹乱化学物質の野生生物に与える影響に関する検討委員会 報告書 平成13年(2001) 3月 別添3-6.

2. 柏木 昭彦柏木 啓子 “両生類の胚および幼生に対するカドミウムの影響”北九州における外因性内分泌撹乱化学物質の野生生物に与える影響に関する検討委員会 報告書 平成13年(2001) 3月 別添21-30.

3. 柏木 昭彦、武石 全慈、倉本 満、柏木 啓子、花田 秀樹、吉里 勝利“北九州山田緑地産ヤマアカガエルに見られる四肢異常の遺伝について” 北九州における外因性内分泌撹乱化学物質の野生生物に与える影響に関する検討委員会 報告書 平成13年(2001) 12月 60-75.

4. 柏木 昭彦 “山田緑地産ヤマアカガエルに見られる四肢異常の遺伝”山田緑地管理委員会「カエル専門委員会」報告書 平成14年(2001) 67-84.

 

 

[井川 助教]

原著論文(英文)

37. Lau Q, Igawa T, Minei R, Kosch TA, Satta Y. Transcriptome analyses of immune tissues from three Japanese frogs (genus Rana) reveals their utility in characterizing major histocompatibility complex class II. BMC Genomics 18: 994 (2017). [ DOI | http | PDF ]

36.  Igawa, T., Nozawa, M., Suzuki, D.G., Reimer, J.D., Morov, A.R., Wang, Y., Henmi, Y., and *Yasui, K.
Evolutionary history of the extant amphioxus lineage with shallow-branching diversification.
Scientific Reports. 7: 1157 (2017). [ DOI | http | PDF ]

35. *Okamiya, H., *Igawa, T., Nozawa, M., Sumida, M., and Kusano, T.
Development and Characterization of 23 Microsatellite Markers for the Montane Brown Frog (Rana ornativentris).
Current Herpetology. 36: 63-68 (2017). [ DOI | http | PDF ]

34. Komaki, S., Lin, S.-M., Nozawa, M., Oumi, S., Sumida, M., and *Igawa, T.
Fine-scale demographic processes resulting from multiple overseas colonization events of the Japanese stream tree frog, Buergeria japonica.
Journal of Biogeography. 44: 1586-1597 (2017). [ DOI | http | PDF ]

33. *Lau, Q., Igawa, T., Komaki, S., and Satta, Y.
Characterization of major histocompatibility complex class I genes in Japanese Ranidae frogs.
Immunogenetics. 68:797-806 (2016).  [ DOI | http | PDF ]

32. Komaki, S., Lau, Q., and Igawa, T.
Living in a Japanese onsen: field observations and physiological measurements of hot spring amphibian tadpoles, Buergeria japonica.
Amphibia-Reptilia. 37: 311-314 (2016). [ DOI | http | PDF ]
(appeared in news sites: Hiroshima Univ., AlphaGalieo, EurekAlert!, ScienceDaily, Asian Scientist and so on.)

31. *Matsunami, M., Igawa, T., Michimae, H., Miura, T., and Nishimura, K.
Population structure and evolution after speciation of the Hokkaido salamander (Hynobius retardatus).
PLoS One. 11(6): e0156815 (2016). [ DOI | http | PDF ]

30. *Sumida, M., Islam, M.M., Igawa, T., Kurabayashi, A., Furukawa, Y., Sano, N., Fujii, T., and Yoshizaki, N.
The first see-through frog created by breeding: description, inheritance patterns, and dermal chromatophore structure.
Scientific Reports. 6: 24431 (2016). [ DOI | http | PDF ]

29. Sultana, N., *Igawa, T.(equal contribution), Islam, M.M., Hasan, M., Alam, M.S., Komaki, S., Kawamura, K., Khan, M.M.R., and Sumida, M.
Inter- and intra-specific genetic divergence of Asian tiger frogs (genus Hoplobatrachus), with special reference to the population structure of H. tigerinus in Bangladesh.
Genes & Genetic Systems. 91: 217-228 (2016).  [ DOI | http | PDF ]

28. Komaki, S., *Igawa, T., Lin, S.-M., and Sumida, M.
Salinity and thermal tolerance of Japanese stream tree frog (Buergeria japonica) tadpoles from island populations.
Herpetological Journal. 26(3): 207-211 (2016). [ DOI | http | PDF ]

27. *Igawa, T., Watanabe, A., Suzuki, A., Kashiwagi, A., Kashiwagi, K., Noble, A., Guille, M., Simpson, D.E., Horb, M.E., Fujii, T., and Sumida, M.
Inbreeding ratio and genetic relationships among strains of the Western clawed frog, Xenopus tropicalis.
PLoS One. 10(7): e0133963 (2015). [ DOI | http | PDF ]

26. Komaki, S., *Igawa, T., Lin, S.-M., Tojo, K., Min, M.-S., and Sumida, M.
Robust molecular phylogeny and palaeodistribution modelling resolve a complex evolutionary history: glacial cycling drove recurrent mtDNA introgression among Pelophylax frogs in East Asia.
Journal of Biogeography. 42:2159-2171 (2015). [ DOI | http | PDF ]

25. *Matsunami, M., Igawa, T., Nozawa, M., Michimae, H., Miura, T., and Nishimura, K.
Development and characterization of 12 microsatellite markers for the Hokkaido salamander (Hynobius retardatus).
Current Herpetology. 34:177-181 (2015). [ DOI | http | PDF ]

24. Kakehashi, R., Igawa, T., and Sumida, M.
Genetic population structure and demographic history of an endangered frog, Babina holsti.
Conservation Genetics. 16:987-1000 (2015). [ DOI | http | PDF ]

23. *Takahara, T., Endo, S., Takada, M., Oba, Y., Nursal, W.I., Igawa, T., Doi, H., Yamada, T., and Okuda, T.
Radiocesium accumulation in the anuran frog, Rana tagoi tagoi, in the forest ecosystems after the Fukushima Nuclear Power Plant accident.
Environmental Pollution. 199:89-94 (2015). [ DOI | http | PDF ]

22. Uno, Y., Nishida, C., Takagi, C., Igawa, T., Ueno, N., Sumida, M., and *Matsuda, Y.
Extraordinary diversity in the origins of sex chromosomes in anurans inferred from comparative gene mapping.
Cytogenetic and Genome Research. 145 (3-4): 218-229. (2015). [ DOI | http | PDF ]

21. *Igawa, T., Komaki, S., Takahara, T., and Sumida, M.
Development and Validation of PCR-RFLP Assay to Identify Three Japanese Brown Frogs of The True Frog Genus Rana.
Current Hepetology. 34: 89-94 (2015).  DOI | http | PDF ]

20. *Igawa, T., Nozawa, M., Nagaoka, M., Komaki, S., Oumi, S., Fujii, T., and Sumida, M.
Microsatellite Marker Development by Multiplex Ion Torrent PGM Sequencing: A Case Study of the Endangered Odorrana narina Complex of Frogs.
Journal of Heredity. 106:131-137 (2015). [ DOI | http | PDF ]

19. Kurniawan, N., Djong, H.T., Maideliza, T., Hamidy, A., Hasan, M., Igawa, T., and Sumida M.
Genetic Divergence and Geographic Distribution of Frogs in Genus Fejervarya from Indonesia Inferred from Mitochondrial 16S rRNA Gene Analysis.
Treubia 41:1-16 (2014). [ DOI | http | PDF ]

18. Sultana, N., *Igawa, T., Nozawa, M., Islam, M.M., Hasan, M., Alam, M.S., Khan, M.M.R., and Sumida, M.
Development and characterization of 27 new microsatellite markers of Indian Bullfrog, Hoplobatrachus tigerinus and its congeneric species.
Genes & Genetic Systems, 89: 137-141, (2014). [ DOI | http | PDF ]

17. Komaki, S., *Igawa, T., Nozawa, M., Lin, S.-M., Oumi, S., and Sumida, M.
Development and characterization of 14 microsatellite markers for Buergeria japonica (Amphibia, Anura, Rhacophoridae).
Genes & Genetic Systems, 89: 35-39, (2014). [ DOI | http | PDF ]

16. Hasan, M., Islam, M.M., Khan, M.R., Igawa, T., Alam, M.S., Djong, H.T., Kruniawan, N., Joshy, H., Sen, Y.H., Belabut, D.M., Kurabayashi, A., Kuramoto, M., and *Sumida, M.
Genetic divergences of South and Southeast Asian frogs: a case study of several taxa based on 16S ribosomal RNA gene data with notes on the generic name Fejervarya.
Turkish Journal of Zoology, 38:1-22, (2014). [ DOI | http | PDF ]

15. *Igawa, T., Oumi, S., Katsuren, S., and Sumida, M.
Population structure and landscape genetics of two endangered frog species of genus Odorrana: different scenarios on two islands.
Heredity, 110:46-56, (2013). [ DOI | http | PDF ]

14. Igawa, T., Sugawara, H., Tado, M., Nishitani, T., Kurabayashi, A., Islam, M., Oumi, S., Katsuren, S., Fujii, T., and *Sumida, M.
An Attempt at Captive Breeding of the Endangered Newt Echinotriton andersoni, from the Central Ryukyus in Japan.
Animals, 3:680-692, (2013).[ DOI | http | PDF ]

13. Kakehashi, R., *Igawa, T., Iwai, N., Shoda-Kagaya, E., and Sumida, M.
Development and characterization of new microsatellite loci in the Otton frog (Babina subaspera) and cross-amplification in a congeneric species, Holst’s frog (B. holsti).
Conservation Genetics Resources, 5(4):1071-1073, (2013). [ DOI | http | PDF ]

12. *Yasui, K., Igawa, T., Kaji, T., and Henmi, Y.
Stable aquaculture of the Japanese lancelet Branchiostoma japonicum for 7 years.
Journal of experimental zoology. Part B, Molecular and developmental evolution, 320B:538-547, (2013). [ DOI | http | PDF ]

11. Hasan, M., Islam, M.M., Khan, M.M.R., Alam, M.S., Kurabayashi, A., Igawa, T., Kuramoto, M., and *Sumida, M.
Cryptic Anuran Biodiversity in Bangladesh Revealed by Mitochondrial 16S rRNA Gene Sequences.
Zoological science, 29(3):162-72, (2012). [ DOI | http | PDF ]

10. Kim, H.L., Iwase, M., Igawa, T., Nishioka, T., Kaneko, S., Katsura, Y., Takahata, N., and *Satta, Y.
Genomic structure and evolution of multigene families: “flowers” on the human genome.
International journal of evolutionary biology, 2012:917678, (2012). [ DOI | http | PDF ]

9. Sugawara, H., Igawa, T., Iwai, N., Yamamuro, K., Oumi, S., and *Sumida, M.
Isolation and characterization of ten microsatellite loci of endangered Anderson’s crocodile newt, Echinotriton andersoni.
Conservation Genetics Resources, 4(3):595-598, (2012). [ DOI | http | PDF ]

8. Igawa, T., Okuda, M., Oumi, S., Katsuren, S., Kurabayashi, A., Umino, T., and *Sumida, M.
Isolation and characterization of twelve microsatellite loci of endangered Ishikawa’s frog (Odorrana ishikawae).
Conservation Genetics Resources, 3(3):421-424, (2011). [ DOI | http | PDF ]

7. *Sumida, M., Satou, N., Yoshikawa, N., Kurabayashi, A., Islam, M.M., Igawa, T., Oumi, S., Katsuren, S., Ota, H., Shintani, N., Fukuniwa, H., Sano, N., and Fujii, T.
Artificial Production and Natural Breeding of the Endangered Frog Species Odorrana ishikawae, with Special Reference to Fauna Conservation in the Laboratory.
Zoological science, 28(11):834-839, (2011). [ DOI | http | PDF ]

6. Kim, H.L., Igawa, T. (equal contribution), Kawashima, A., Satta, Y., and *Takahata, N.
Divergence, demography and gene loss along the human lineage.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 365(1552):2451-2457 (2010). [ DOI | http | PDF ]

5. Kurniawan, N., Islam, M.M., Djong, T.H., Igawa, T., Daicus, M.B., Yong, H. Sen, Wanichanon, R., Khan, M.M.R., Iskandar, D.T., Nishioka, M., and Sumida, M.
Genetic divergence and evolutionary relationship in Fejervarya cancrivora from Indonesia and other Asian countries inferred from allozyme and MtDNA sequence analyses.
Zoological science, 27(3):222-33, (2010). [ DOI | http | PDF ]

4. Alam, M.S., Igawa, T., Khan, M.M.R., Islam, M.M., Kuramoto, M., Matsui, M., Kurabayashi, A., and Sumida, M.
Genetic divergence and evolutionary relationships in six species of genera Hoplobatrachus and Euphlyctis (Amphibia: Anura) from Bangladesh and other Asian countries revealed by mitochondrial gene sequences.
Molecular phylogenetics and evolution, 48(2):515-527 (2008). [ DOI | http | PDF ]

3. Igawa, T., Kurabayashi, A., Usuki, C., Fujii, T., and *Sumida, M.
Complete mitochondrial genomes of three neobatrachian anurans: A case study of divergence time estimation using different data and calibration settings.
Gene, 407(1-2):116-129 (2008). [ DOI | http | PDF ]

2. *Sumida, M., Kotaki, M., Islam, M.M., Djong, T.H., Igawa, T., Kondo, Y., Matsui, M., Anslem, D.S., Khonsue, W., and Nishioka, M.
Evolutionary relationships and reproductive isolating mechanisms in the rice frog (Fejervarya limnocharis) species complex from Sri Lanka, Thailand, Taiwan and Japan, inferred from mtDNA gene sequences, allozymes, and crossing experiments.
Zoological science, 24(6):547-562 (2007). [ DOI | http | PDF ]

1. Igawa, T., Kurabayashi, A., Nishioka, M. & Sumida, M.
Molecular phylogenetic relationship of toads distributed in the Far East and Europe inferred from the nucleotide sequences of mitochondrial DNA genes.
Molecular phylogenetics and evolution, 38(1):250-260 (2006). [ DOI | http | PDF ]

 

 

[ 柏木啓子 研究員]

原著論文・総説
1.Goto-Inoue, N., Sato, T., Mizuki, M., Kashiwagi, A., Kashiwagi, K., Sugiura, Y., Sugiyama, E., Suematsu, M. and Mori, T.
Utilizing mass spectrometry imaging to map the thyroid hormones triiodothyronine and thyroxine in Xenopus tropicalis tadpoles.
Anal. Bioanal. Chem., 410:1333-1340 (2018) (doi: 10.1007/s00216-017-0775-y).

2. Mori, J., Sanoh, S., Kashiwagi, K., Hanada, H., Shigeta, M., Suzuki, K.T., Yamamoto, T., Kotake, Y., Sugihara, K., Kitamura, S., Kashiwagi, A. and Ohta, S.
Developmental changes in drug-metabolizing enzyme expression during metamorphosis of Xenopus tropicalis.
J. Toxicol. Sci., 42(5):605-613(2017) ( doi: 10.2131/jts.42.605)

3. Mori, T., Yanagisawa, Y., Kitani,Y., Yamamoto,G., Goto-Inoue1,N. Kimura,T., Kashiwagi, K. and Kashiwagi, A.
The constant threat from a non-native predator increases tail muscle and fast-start swimming performance in Xenopus tadpoles
Biology Open, 6: 1726-1733 (2017) (doi:10.1242/bio.029926)

4. Goto-Inoue,N., Kashiwagi,A., Kashiwagi,K. and Tsukasa Mori.
Metabolomic approach for identifying and visualizing molecular tissue markers in tadpoles of Xenopus tropicalis by mass spectrometry imaging.
Biology Open, 5: 1252-1259 (2016) (doi:10.1242/bio.O19646)

5. Shigeta, M., Sakane,Y., Iida, M., Suzuki, M., Kashiwagi, K., Kashiwagi, A., Fujii, S., Yamamoto, T. and Suzuki, K.T.
A streamlined workflow for rapid and efficient gene disruption by CRISPR-Cas9 in Xenopus tropicalis founders.
Genes Cells. (2016)( doi: 10.1111/gtc.12379.)

6. Nakade, S., Sakuma, T., Sakane, Y., Hara, Y., Kurabayashi, A., Kashiwagi, K., Kashiwagi,A.,
Yamamoto, T. and Obara, M.
Homeolog-specific targeted mutagenesis in Xenopus laevis using TALENs.
In Vitro Cellular & Developmental Biology─Animal, 51: 879-884(2016)

7. Igawa,T., Watanabe,A., Suzuki, A., Kashiwagi, A., Kashiwagi,K., Noble,A., Guille,M., Simpson, D.E., Horb, M.E., Fujii, T. and Sumida, M.
Inbreeding ratio and genetic relationships among strains of the Western Clawed Frog, Xenopus tropicalis.
PLoS ONE, 10(7): e0133963 (2015)

8. Hanada, H., Kashiwagi, K., Suzuki, K., Yamamoto, T. and Kashiwagi, A.
Suppression of anuran metamorphosis by synthetic chemicals.
Genetic Diversity, Neural Development and Environmental Influences. p.73-88. (Nova,Sweden). (2014)

9. Hanada , H., Kobuchi, H., Yamamoto, M., Kashiwagi, K., Katsu, K., Utsumi, T., Kashiwagi, A., Sasaki, J., Inoue, M. and Utsumi, K.
Acetyl-L-carnitine suppresses thyroid hormone-induced and spontaneous anuran tadpole tail shortening.
Hereditas, 150: 1-9. (2013)

10. Suzuki, K., Isoyama, Y., Kashiwagi, K., Sakuma, T., Ochiai, H., Sakamoto, N., Furuno, N., Kashiwagi, A. and Yamamoto, T.
High efficiency TALENs enable F0 functional analysis by targeted gene disruption in Xenopus laevis embryos.
Biology Open, BIO_2013_3855.3d. doi: 10. 1242/bio.20133855: 1-5. (2013)

11. Sakane,Y., Sakuma,T., Kashiwagi,K., Kashiwagi,A., Yamamoto,T. and Suzuki, K.
Targeted mutagenesis of multiple and paralogous genes in Xenopus laevis using two pairs
oftranscription activator-like effector nucleases.
Dev. Growth Diff., 2014: 108-114.(2013)

12. Sakuma, T., Hosoi, S., Woltjen, K. I., Kashiwagi, K., Wada, H., Ochiai, H., Miyamoto,
T., Kawai, N., Sasakura, Y., Matsuura, S., Okada ,Y., Kawahara, A., Hayashi, S. and Yamamoto, T.
Efficient TALEN construction and evaluation methods for human cell and animal applications.
Genes Cells,18:315-326 (2013)

13. Yanagisawa, M., Kashiwagi, K., Hanada, H., Shinkai, T., Yoshitome, S., Kubo, H., Sakai, M.,
Fujii, H., Yamashita, M., Kashiwagi, A., Watanabe, M. and Furuno, N.
Hypergravity specifically affects anterior head formation in early Xenopus embryos.
Biol. Sci. Space, 26: 47-52.(2012)

14. Yanagisawa, M., Kashiwagi, K., Hanada, H., Shinkai, T., Yoshitome, S., Kubo, H., Itai, M.,
Fujii, H., Yamashita, M., Kashiwagi, A., Watanabe, M. and Furuno, N.
Analysis of the head-defects caused by hypergravity in early Xenopus embryos.
Biol. Sci. Space, 26: 1-6. (2012)

15. Yanagisawa, M., Furuno, N., Watanabe, M., Kashiwagi, K., Hanada, H., Shinkai, T., Yoshitome,
S., Kubo, H., Itai, M., Fujii, H., Suzuki, K., Yamashita, M. and Kashiwagi, A.
Hypergravity specifically effects head formation in the Xenopus embryos raseid under hypergravity
condition.
Space Utili. Res., 28:172-175. (2012)

16. Fujiwara, Y., Kashiwagi, K., Nakagawa, M., Shinkai, T., Yanagisawa, M., Furuno, N., Hanada,
H., Suzuki, K., Katsu, K., Yamashita, M., Yamamoto, T., Tanimoto, Y. and Kashiwagi, A.
Effects of magnetically controllled microgravity and hypergravity environment on amphibian
behavior.
Space Utili. Res., 28:176-179. (2012)

17. Yanagisawa, M., Furuno, N., Watanabe, M., Kashiwagi, K., Hanada, H., Shinkai, T.,
Yoshitome, S., Kubo, H., Itai, M., Fujii, H., Suzuki, K.T., Yamashita, M. and Kashiwagi, A.
Molecular analyses of the head-defects in the Xenopus embyos rased under hypergravity conditions.
Space Utili. Res., 27: 198-200. (2011)

18. Furuno, N., Futsuki, D., Kawasaki, T., Shiraga, M., Tanimoto,Y., Kashiwagi, K., Suzuki, K.T., Yamashita, M.and Kashiwagi, A.
Effect of strong static magnetic fields on the amphibian life cycle – Effect on oocyte maturation of
Silurana tropicalis.
Space Utiliz, Res., 26: 228-231. (2010)

19. Kashiwagi, K., Fujiwara, Y., Sakao, S., Furuno, N., Yanagisawa, M., Hanada, H., Tanimoto, Y.,
Yamashita, M., Watanabe, M., Shinkai, T., Yoshitome, S., Kubo, H., Sakai, M., Fujii, H., Naitoh,
T., Suzuki, K. and Kashiwagi , A.
Effect of strong static magnetic fields on the amphibian life cycle – morphological and molecular
biological analyses of early development.
Space Utiliz, Res., 26: 232-235.(2010)

20. Kashiwagi, K., Kashiwagi, A., Kurabayashi, A., Hanada, H., Nakajima, K., Okada, M., Takase, M. and Yaoita, Y.
Xenopus tropicalis: An ideal experimental animal in amphibia.
Exp. Anim., 59(4): 395-405. (2010)

21. Suzuki, K.T., Kashiwagi, K., Ujihara, M., Marukane, T., Tazaki, A., Watanabe, K., Mizuno, N., Ueda, Y., Kondoh, H., Kashiwagi, A. and Mochii, M.
Characterization of a novel type I keratin gene and generation of transgenic lines with fluorescent reporter genes driven by its promoter/enhancer in Xenopus laevis .
Dev. Dyn., 239: 3172-3181.(2010)

22. Furuno, N., Futsuki, D., Kawasaki T., Shiraga, M., Tanimoto, Y., Kashiwagi, K., Suzuki, K.T., Yamashita, M. and Kashiwagi, A.
Effect of strong static magnetic fields on amphibian life cycle──Effect on oocyte maturation in Xenopus topicalis─
Space Utiliz. Res., 26: 228-231 (2010)

23. Oka, T., Miyahara, M.,Yamamoto, J., Mitui, N., Fujii, T., Tooi, O., Kashiwagi, K., Takase,M., Kashiwagi, A. and Iguchi, T.
Application of metamorphosis assay to a native Japanese amphibian species, Rana rugosa, for assessing effects of thyroid system affecting chemicals.
Ecotoxicol. Environ. Saf., 64: 281-287. (2009)

24. Kashiwagi, K., Furuno, N., Hanada, H., Kitamura, S., Utsumi, K., Taniguchi,K., Ohta, S., Sugihara, K., Suzuki, K. and Kashiwagi, A.
Review. Disruption of thyroid hormone function by environmental pollutants.
J. Health Sci., 55: 147-160 (2009)

25. Suzuki, K., Machiyama, F., Nishino, S., Watanabe, Y., Kashiwagi, K., Kashiwagi, A. and Yoshizato, K.
Molecular features of thyroid hormone-regulated skin remodeling in Xenopus laevis during metamorphosis.
Dev. Growth Differ., 51: 411-427. (2009)

26. Watanabe, M., Yanagisawa, M., Furuno, N., Kashiwagi, K., Shinkai, T., Hanada, H., Yoshitome, S., Kubo, H., Itai, M., Fujii, H., Yamashita, M. and Kashiwagi, A.
Analysis of Head-Defects in Xenopus Embryos Raised under Hypergravity Condition.
Space Utiliz. Res., 25: 155-158. (2009)

27. Kashiwagi,A., Utsumi,K., Kashiwagi, K., Ohta, S., Sugihara, K., Hanada, H. and Kitamura, S.
Minireview. Effects of endocrine disrupting chemicals on amphibian metamorphosis and mitochondrial membrane permeability transition.
J. Health Sci., 54: 273-280. (2008)

28. Kashiwagi, K., Hanada, H., Yamamoto, T., Goto, Y., Furuno, N., Kitamura,S., Ohta,S., Sugihara, K., Taniguchi, K, Tooi, O., Suzuki, K.T., Yoshizato,K. and Kashiwagi, A.
2-Hydroxy-4-methoxybenzophenone(HMB) and 2,4,4’-trihydroxybenzophenone (THB) suppress amphibian metamorphosis.
Progr. Safe. Technol., 7: 970-976. (2008)

29. Oka, T., Tooi, O., Mitsui, N., Miyahara, M., Ohnishi, Y., Takase, M., Kashiwagi, K., Kashiwagi, A. Shinkai, T., Santo, N. and Iguchi, T.
Effect of atrazine on metamorphosis and sexual differentiation in Xenopus laevis.
Aquatic Toxicol., 87: 215-226. (2008)

30.Shinkai, T., Kashiwagi, A., Kashiwagi, K., Furuno, N., Hanada, H., Kubo, H., Yoshitome, S., Watanabe, M., Fujii, H., Itai, M. and Yamashita, M.
Effects of Thyroxine on the Mulfunction of Pituitary-Thyroid Axis by Exposing Hypergravity in the Tropical clawed frog Xenopus tropicalis.
Space Utiliz. Res., 24: 242-245 (2008) .

31. Furuno, N., Tazawa, I., Kashiwagi, K., Shinkai, T., Yoshitome, S., Watanabe, M., Yamashita,
M. and Kashiwagi, A.
Effects of hypergravity on oocyte maturation in Xenopus laevis, Part II.
Space Utliz. Res., 23: 311-313. (2007)

32. Shinkai, T., Matsuda, M., Kashiwagi, A., Kashiwagi, K., Furuno, N., Urano, S., Kubo, H.,
Sakai,M., Fujii, H. and Yamashita, M.
Effects of hypergravity of hypothalamus-pituitary axis in the frog, Xenopus laevis.
Space Utliz. Res., 23, 314-317. (2007)

33. Kashiwagi, A., Kashiwagi, K., Saito, S., Date-Ito, A., Ichikawa, M., Mori, Y., and Hagino-
Yamagishi, K.
Stable knock-down of vomeronasal receptor genes in transgenic Xenopus tadpoles.
Biochem. Biophys. Res. Commun., 345: 140-147. (2006)

34. Goto, Y., Kitamura, S., Kashiwagi, K., Oofusa, K., Tooi, O., Yoshizato, K., Sato, J., Ohta, S.
and Kashiwagi, A.
Suppression of amphibian Metamorphosis by bisphenol A and related chemical substances.
J. Health Sci., 52: 160-168. (2006)

35. Tazawa, I., Kashiwagi, A., Kashiwagi, K. and Furuno. N.
Effects of hypergravity on oocyte maturation in Xenopus laevis.
Biol. Sci. Space, 19: 242-244. (2006)

36. Kawakami, S., Kashiwagi, K., Furuno, N., Yamashita, M. and Kashiwagi , A.
Effects of hypergravity environments on amphibian development, gene expression and apoptosis.
Comp. Biochem. Physiol., part A. 145: 65-72. (2006)

37. Kawakami, S., Kashiwagi, K., Furuno, N., Yamashita, M., Kashiwagi , A. and Tanimoto, Y.
Effects of strong static magnetic fields on amphibian development and gene expression.
Jap. J. Appl. Phys., 45: 6055-6056. (2006)

38. Kawakami,S.,Kashiwagi, K., Furuno, N.,Kashiwagi, A.,Yamashita, M. and Tanimoto,Y.
Influence of hypergravity and high magnetic field on the development and gene
expression of Xenopus laevis.
Jap. J. Appl. Phys., 59: EA62. (2006)

39. Shinkai, T., Kashiwagi, A., Kashiwagi, K., Matsuda, K., Urano, S., Sato, H., Kubo, H., Furuno,
N., Sakai, M., Watanabe, M., Yoshitome, S., Fujii, H. and Yamashita, M.
Effects of hypergravity on pituitary-target organs in the frog, Xenopus laevis.
Biol. Sci. Space, 20: 40-43. (2006)

40. Furuno, N.,Tazawa, I., Kashiwagi, K., Kawakami, S., Shinkai, T., Yamashita, M. and Kashiwagi, A.
The effect of hypergravity on bipolar spindle formation on meiosis II in Xenopus oocytes.
Biol. Sci. Space, 20: 92-94. (2006)

41. Furuno N., Tazawa I., Kashiwagi K., Kawakami S., Yoshitom, S., Watanabe M., Yamashita, M.
and Kashiwagi, A.
Effects of hypergravity on oocyte maturation in Xenopus laevis.-I
Space Utiliz. Res., 22: 228-230. (2006)

42. Shinkai, T., Kashiwagi, A., Kashiwagi, K., Furuno, N., Urano, S., Sato, H., Kubo, H., Itai, M.,
Watanabe, M., Yoshitome, S., Fujii, H. and Yamashita, M.
Effects of hypergravity on pituitary-target organ axes in the African clawed frog Xenopus laevis.
Space Utiliz. Res., 22: 231-234. (2006)

43. Mitsui, N., Fujii, T., Miyahara, M., Oka, T., Kashiwagi, A., Kashiwagi, K., Hanada, H.,
Urushitani, H., Santo, N., Tooi, O. and Iguchi, T.
Development of metamorphosis assay Silurana tropicalis for the detection of thyroid
system-disrupting chemicals
Ecotoxicol. Environ. Safety, 64: 281-287. (2006)

44. Kashiwagi, K., Shinkai, T., Kajii, E., and Kashiwagi, A.
The effect of reactive oxygen species on amphibian aging.
Comp. Biochem. Physiol. C 140: 197-120. (2005)

45. Kashiwagi, A., Furuno N., Kashiwagi K., Hanada H., Kawakami S., Watanabe M. and Yamashita M.
Effects of gravity on the amphibian life cycle──morphological and molecular biological analyses of early development, morphogenesis and metamorphosis
Space Utiliz. Res., 21: 270-273. (2005)

46. Kitamura, S., Kato, T., Iida, M., Jinno, N., Suzuki, T., Ohta, S., Fujimoto, N., Hanada, H.,
Kashiwagi, K. and Kashiwagi, A.
Anti-thyroid hormonal activity of tetrabromobisphenol A, a flame retardant, and related compounds:
affinity to the mammalian thyroid hormone receptor, and effect on tadpole metamorphosis.
Life Sci., 76: 1589-1601. (2005)

47. Kashiwagi, A., Kawakami, S., Hanada, H., Kashiwagi, K. and Gusev, O.
Apoptosis, changes in body morphology and function, and effects of gravity during
amphibian metamorphosis.-IV
Space Utiliz. Res., 20: 57-60 (2004)

48. Kashiwagi, A., Kashiwagi, K., Hanada, H., Kubo, H., Shinkai, T., Fujii, H. and
Yamashita, M.
Apoptosis, changes in body morphology and function, and effects of gravity during
amphibian metamorphosis.
Space Utiliz. Res., 19: 45-48. (2003)

49. Kashiwagi, A., Hanada, H., Kawakami, S., Kubo, H., Shinkai, T., Fujii, H. and Kashiwagi, K.
Effects of high gravity on amphibian development.
Biol. Sci.Space, 17: 215-216. (2003)

50. Oofusa, K., Tooi, O., Kashiwagi, A., Kashiwagi, K., Kondo, Y., Obara. M. and Yoshizato, K.
Metal ion-responsive transgenic Xenopus laevis as an environmental monitoring animal.
Environ. Toxicol. Pharmacol., 13: 153-159. (2003)

51. Kashiwagi, A., Kashiwagi, K., Hanada, H., Kubo, H., Shinkai, T., Fujii, H. and
Yamashita, M.
Apoptosis, changes in body morphology and function, and effects of gravity during
amphibian metamorphosis.-III
Space Utiliz. Res., 18: 109-112. (2002)

52. Oofusa, K., Tooi, O., Kashiwagi, A., Kashiwagi, K., Kondoh, Y., Watanabe, Y., Sawada, T.,
Fujikawa, T. and Yoshizato, K.
Expression of thyroid hormone receptor beta gene assayed by transgenic Xenopus laevis carrying its
promoter sequences.
Mol. Cell. Endocrinol.,181: 97-110. (2001)

53. Kashiwagi , K. and Kashiwagi , A.
Effects of cadmium chloride on amphibians.
Zoological Science, 18(Suppl), 30. (2001)

54. Kashiwagi, A., Kashiwagi, K., Kubo, H., Shinkai, T. and Fujii, H.
Apoptosis, changes in body morphology and function, and effects of gravity during amphibian metamorphosis.-II
Space Utiliz. Res., 17: 84-87. (2001)

55. Kashiwagi, A., Kashiwagi, K., Takase, M., Hanada, H., Yamashita, M., Naitoh, T. and
Nakamura, M.
Inhibitor and temperature effect on catalase in the liver of adult diploid and haploid Rana rugosa.
Comp. Biochemi. Physiol., B119: 235-239. (1998)

56. Kashiwagi, A., Kashiwagi, K., Takase, M., Hanada, H. and Nakamura, M.
Comparison of catalase in diploid and haploid Rana rugosa using heat and chemical inactivation techniques.
Comp. Biochem. Physiol., B118: 499-503. (1997)

57. Kashiwagi, A. and Kashiwagi, K.
Comparison of liver peroxisomal enzyme activity changes during development of diploid and
haploid anurans.
Comp. Biochem. Physiol., B113: 533-536. (1996)

58. Kashiwagi, K. and Kashiwagi, A.
Comparison of peroxisomal enzyme activity changes in the tail of diploid and haploid anuran
tadpoles during metamorphosis.
Compa. Biochem. Physiol., B115: 399-403. (1996)

59. Kashiwagi, K. and Kashiwagi, A.
Artificially produced chimeras between haploids and diploids in Japanese anurans.
Sci. Rep. Lab. Amphibian Biol., Hiroshima Univ., 12: 37-54. (1993)

60. Kashiwagi, K.
Production of triploids and their reproduction capacity in Rana rugosa.
Sci.Rep. Lab. Amphibian Biol. Hiroshima Univ., 12: 23-36. (1993)

61. Kashiwagi, K.
Gynogenetic diploids in Rana rugosa and their offspring.
Sci.Rep. Lab. Amphibian Biol. Hiroshima Univ., 12: 1-22. (1993)

62. Kashiwagi,K.
Mature haploids and their reproductive capacity in Rana rugosa.
Sci. Rep. Lab. Amphibian Biol. Hiroshima Univ., 4: 217-237. (1980)

著書
1.柏木 昭彦、花田 秀樹、柏木啓子、矢吹 宗久、菅野 智子、石坂 瑠美、竹原 良記、佐々
木順造、井上 正康、内海 耕慥.
生命誕生と生物の生存戦略.
日本アクセル・シュプリンガー出版, メディカルトリビューンブックス (1998)

2. 大房 健、戸笈 修、柏木昭彦、柏木啓子、近藤育志、吉里勝利.
「トランスジェニックカエルの作製方法」
実験医学18、795-801. (2000)

3. 大房 健、戸笈 修、柏木昭彦、柏木啓子、近藤育志、吉里勝利
「トランスジェニックカエルの作製方法」
実験医学別冊 クローズアップ実験法 78-84. (2002)

4. 柏木昭彦、柏木啓子、古野伸明、新海 正.
Biophilia Special 宇宙での生物観察、実験4 カエルを宇宙へ-アフリカツメガエルを用いた宇宙実験
Biophilia 3, 26-31. ( 2007)

報告書

1. 柏木啓子
「板櫃川で発見された後肢欠損ガエルの発生原因について」 北九州市環境局 (2011) 8月

2. 柏木 昭彦、花田 秀樹、柏木 啓子、吉里 勝利、武石 全慈、倉本 満、小野 勇一、門上 希和夫“カエル細胞に及ぼすトリニトロトルエンの細胞遺伝学的影響” 北九州における外因性内分泌撹乱化学物質の野生生物に与える影響に関する検討委員会 報告書 平成13年(2001) 3月 別添3-6.

3. 柏木 昭彦、柏木 啓子“両生類の胚および幼生に対するカドミウムの影響”北九州における外因性内分泌撹乱化学物質の野生生物に与える影響に関する検討委員会 報告書 平成13年(2001) 3月 別添21-30.

4. 柏木 昭彦、武石 全慈、倉本 満、柏木 啓子、花田 秀樹、吉里 勝利“北九州山田緑地産ヤマアカガエルに見られる四肢異常の遺伝について” 北九州における外因性内分泌撹乱化学物質の野生生物に与える影響に関する検討委員会 報告書 平成13年(2001) 12月 60-75.