{"id":4440,"date":"2025-11-10T12:54:34","date_gmt":"2025-11-10T03:54:34","guid":{"rendered":"https:\/\/amphibian.hiroshima-u.ac.jp\/~oginolab\/?p=4440"},"modified":"2025-11-10T12:54:36","modified_gmt":"2025-11-10T03:54:36","slug":"%e7%b4%b0%e8%83%9e%e6%8e%a5%e7%9d%80%e9%9d%a2%e3%81%a7%e4%ba%92%e3%81%84%e3%81%ae%e5%8f%8e%e7%b8%ae%e5%8a%9b%e3%82%92%e6%84%9f%e7%9f%a5%e3%81%97%e5%8a%9b%e5%ad%a6%e7%9a%84%e6%83%85%e5%a0%b1%e3%82%92","status":"publish","type":"post","link":"https:\/\/amphibian.hiroshima-u.ac.jp\/~oginolab\/archives\/4440","title":{"rendered":"\u7d30\u80de\u63a5\u7740\u9762\u3067\u4e92\u3044\u306e\u53ce\u7e2e\u529b\u3092\u611f\u77e5\u3057\u529b\u5b66\u7684\u60c5\u5831\u3092\u4f1d\u9054\u3059\u308b\u4ed5\u7d44\u307f\u306e\u89e3\u660e"},"content":{"rendered":"\n<p>\u9234\u6728\u8aa0\u51c6\u6559\u6388\u306f\u3001\u4e5d\u5dde\u5927\u5b66\u5927\u5b66\u9662\u533b\u5b66\u7814\u7a76\u9662\u751f\u5316\u5b66\u5206\u91ce\u306e\u677e\u6ca2\u5065\u53f8\u8b1b\u5e2b\u3001\u6c60\u30ce\u5185\u9806\u4e00\u6559\u6388\u3089\u3068\u306e\u5171\u540c\u7814\u7a76\u306b\u3088\u308a\u3001\u4e0a\u76ae\u7d30\u80de\u304c\u7d30\u80de\u63a5\u7740\u9762\u3067\u4e92\u3044\u306e\u53ce\u7e2e\u529b\u3092\u611f\u77e5\u3057\u529b\u5b66\u7684\u60c5\u5831\u3092\u4f1d\u9054\u3059\u308b\u4ed5\u7d44\u307f\u3092\u660e\u3089\u304b\u306b\u3057\u307e\u3057\u305f\u3002\u3053\u306e\u6210\u679c\u306f\u3001\u56fd\u969b\u79d1\u5b66\u8a8c\u306e\u7c73\u56fd\u79d1\u5b66\u30a2\u30ab\u30c7\u30df\u30fc\u7d00\u8981\uff08PNAS\uff09\u306b\u63b2\u8f09\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p>\u79c1\u305f\u3061\u306e\u304b\u3089\u3060\u3092\u69cb\u6210\u3059\u308b\u3055\u307e\u3056\u307e\u306a\u81d3\u5668\u306f\u3001\u4e0a\u76ae\u7d30\u80de\u306e\u30b7\u30fc\u30c8\u304c\u6e7e\u66f2\u3059\u308b\u3053\u3068\u3067\u7ba1\u72b6\u3084\u888b\u72b6\u306e\u69cb\u9020\u3092\u5f62\u6210\u3057\u307e\u3059\u3002\u3053\u306e\u3088\u3046\u306a\u4e0a\u76ae\u7d30\u80de\u30b7\u30fc\u30c8\u306e\u5909\u5f62\u306f\u3001\u7d30\u80de\u63a5\u7740\u69cb\u9020\u3092\u88cf\u6253\u3061\u3059\u308b\u30a2\u30af\u30c8\u30df\u30aa\u30b7\u30f3\u7dda\u7dad\u306e\u53ce\u7e2e\u306b\u3088\u3063\u3066\u8d77\u3053\u308a\u307e\u3059\u3002\u3057\u304b\u3057\u3001\u3053\u306e\u30a2\u30af\u30c8\u30df\u30aa\u30b7\u30f3\u7dda\u7dad\u306e\u53ce\u7e2e\u304c\u3069\u306e\u3088\u3046\u306b\u5236\u5fa1\u3055\u308c\u3066\u3044\u308b\u306e\u304b\u306b\u3064\u3044\u3066\u306f\u3001\u4e0d\u660e\u306a\u70b9\u304c\u591a\u304f\u6b8b\u3055\u308c\u3066\u3044\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p>\u672c\u7814\u7a76\u306b\u304a\u3044\u3066\u7814\u7a76\u30b0\u30eb\u30fc\u30d7\u306f\u3001\u57f9\u990a\u7d30\u80de\u3092\u7528\u3044\u305f\u30e9\u30a4\u30d6\u30bb\u30eb\u30a4\u30e1\u30fc\u30b8\u30f3\u30b0\u89e3\u6790\u304a\u3088\u3073\u7d30\u80de\u751f\u7269\u5b66\u89e3\u6790\u306b\u3088\u308a\u3001\u8db3\u5834\u30bf\u30f3\u30d1\u30af\u8cea\u3067\u3042\u308bHomer\u304c\u4e0a\u76ae\u7d30\u80de\u306e\u9802\u70b9\u63a5\u5408\u90e8\u306b\u5b58\u5728\u3057\u3001\u6a5f\u68b0\u7684\u306a\u5f35\u529b\u3092\u611f\u77e5\u3057\u3066\u5c40\u6240\u7684\u306a\u30ab\u30eb\u30b7\u30a6\u30e0\u30b7\u30b0\u30ca\u30eb\u3092\u5f15\u304d\u8d77\u3053\u3059\u3053\u3068\u3067\u3001\u7d30\u80de\u9aa8\u683c\uff08\u30a2\u30af\u30c8\u30df\u30aa\u30b7\u30f3\u7dda\u7dad\uff09\u306e\u53ce\u7e2e\u529b\u3092\u8abf\u7bc0\u3059\u308b\u5f79\u5272\u3092\u679c\u305f\u3059\u3053\u3068\u3092\u767a\u898b\u3057\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p>\u307e\u305f\u3001\u30a2\u30d5\u30ea\u30ab\u30c4\u30e1\u30ac\u30a8\u30eb\u80da\u3092\u7528\u3044\u305f\u89e3\u6790\u306b\u3088\u308a\u3001Homer\u306e\u6a5f\u80fd\u304c\u795e\u7d4c\u7ba1\u9589\u9396\uff08\u521d\u671f\u80da\u3067\u8133\u3084\u810a\u9ac4\u306e\u3082\u3068\u3068\u306a\u308b\u7ba1\u3092\u5f62\u6210\u3059\u308b\u904e\u7a0b\uff09\u306b\u5fc5\u9808\u3067\u3042\u308a\u3001\u305d\u306e\u963b\u5bb3\u304c\u795e\u7d4c\u7ba1\u9589\u9396\u306e\u5931\u6557\u3092\u5f15\u304d\u8d77\u3053\u3059\u3053\u3068\u3092\u898b\u51fa\u3057\u307e\u3057\u305f\u3002\u795e\u7d4c\u7ba1\u9589\u9396\u306f\u8133\u3084\u810a\u9ac4\u306e\u767a\u751f\u306b\u5fc5\u9808\u306e\u73fe\u8c61\u3067\u3042\u308a\u3001\u305d\u306e\u7570\u5e38\u306f\u4e8c\u5206\u810a\u690e\u3084\u6c34\u982d\u75c7\u306a\u3069\u306e\u5148\u5929\u6027\u75be\u60a3\u306b\u3064\u306a\u304c\u308a\u307e\u3059\u3002\u3053\u306e\u7d50\u679c\u306f\u3001Homer\u304c\u7d30\u80de\u7a2e\u3092\u8d85\u3048\u3066\u767a\u751f\u904e\u7a0b\u306b\u304a\u3044\u3066\u3082\u91cd\u8981\u306a\u5f79\u5272\u3092\u679c\u305f\u3057\u3066\u3044\u308b\u3053\u3068\u3092\u793a\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>Homer\u3092\u4ecb\u3057\u305f\u529b\u5b66\u7684\u60c5\u5831\u306e\u4f1d\u9054\u6a5f\u69cb\u306f\u3001\u4e0a\u76ae\u7d30\u80de\u304c\u7d30\u80de\u6975\u6027\u3092\u4fdd\u3063\u305f\u307e\u307e\u5c40\u6240\u7684\u306a\u529b\u5b66\u5fdc\u7b54\u3092\u5236\u5fa1\u3067\u304d\u308b\u5de7\u5999\u306a\u4ed5\u7d44\u307f\u3067\u3042\u308b\u3068\u8003\u3048\u3089\u308c\u307e\u3059\u3002\u672c\u6210\u679c\u306f\u3001\u4e0a\u76ae\u7d44\u7e54\u306b\u304a\u3051\u308b\u7d30\u80de\u5354\u8abf\u30e1\u30ab\u30cb\u30ba\u30e0\u306e\u7406\u89e3\u3092\u6df1\u3081\u3001\u767a\u751f\u751f\u7269\u5b66\u3084\u518d\u751f\u533b\u7642\u306b\u65b0\u305f\u306a\u77e5\u898b\u3092\u3082\u305f\u3089\u3059\u3053\u3068\u304c\u671f\u5f85\u3055\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p>K. Matsuzawa, M. Suzuki, Y. Cho, R. Fujinaga, &amp; J. Ikenouchi, A steady-state pool of calcium-dependent actin is maintained by Homer and controls epithelial mechanosensation, Proc. Natl. Acad. Sci. U.S.A. 122 (43) e2509784122,<\/p>\n\n\n\n<p><a href=\"https:\/\/www.pnas.org\/doi\/10.1073\/pnas.2509784122\">https:\/\/www.pnas.org\/doi\/10.1073\/pnas.2509784122<\/a><\/p>\n\n\n\n<p>\u5e83\u5cf6\u5927\u5b66\u30d7\u30ec\u30b9\u30ea\u30ea\u30fc\u30b9\u8a18\u4e8b\uff1a<a href=\"https:\/\/www.hiroshima-u.ac.jp\/news\/93678\">https:\/\/www.hiroshima-u.ac.jp\/news\/93678<\/a><\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"610\" height=\"1000\" src=\"https:\/\/amphibian.hiroshima-u.ac.jp\/~oginolab\/wp-content\/uploads\/2025\/11\/1-small.jpg\" alt=\"\" class=\"wp-image-4441\" srcset=\"https:\/\/amphibian.hiroshima-u.ac.jp\/~oginolab\/wp-content\/uploads\/2025\/11\/1-small.jpg 610w, https:\/\/amphibian.hiroshima-u.ac.jp\/~oginolab\/wp-content\/uploads\/2025\/11\/1-small-183x300.jpg 183w\" sizes=\"auto, (max-width: 610px) 100vw, 610px\" \/><\/figure>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>\u9234\u6728\u8aa0\u51c6\u6559\u6388\u306f\u3001\u4e5d\u5dde\u5927\u5b66\u5927\u5b66\u9662\u533b\u5b66\u7814\u7a76\u9662\u751f\u5316\u5b66\u5206\u91ce\u306e\u677e\u6ca2\u5065\u53f8\u8b1b\u5e2b\u3001\u6c60\u30ce\u5185\u9806\u4e00\u6559\u6388\u3089\u3068\u306e\u5171\u540c\u7814\u7a76\u306b\u3088\u308a\u3001\u4e0a\u76ae\u7d30\u80de\u304c\u7d30\u80de\u63a5\u7740\u9762\u3067\u4e92\u3044\u306e\u53ce\u7e2e\u529b\u3092\u611f\u77e5\u3057\u529b\u5b66\u7684\u60c5\u5831\u3092\u4f1d\u9054\u3059\u308b\u4ed5\u7d44\u307f\u3092\u660e\u3089\u304b\u306b\u3057\u307e\u3057\u305f\u3002\u3053\u306e\u6210\u679c\u306f\u3001\u56fd\u969b\u79d1\u5b66\u8a8c\u306e\u7c73\u56fd\u79d1 [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":3899,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"vkexunit_cta_each_option":"","footnotes":""},"categories":[4],"tags":[],"class_list":["post-4440","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news"],"_links":{"self":[{"href":"https:\/\/amphibian.hiroshima-u.ac.jp\/~oginolab\/wp-json\/wp\/v2\/posts\/4440","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/amphibian.hiroshima-u.ac.jp\/~oginolab\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/amphibian.hiroshima-u.ac.jp\/~oginolab\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/amphibian.hiroshima-u.ac.jp\/~oginolab\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/amphibian.hiroshima-u.ac.jp\/~oginolab\/wp-json\/wp\/v2\/comments?post=4440"}],"version-history":[{"count":1,"href":"https:\/\/amphibian.hiroshima-u.ac.jp\/~oginolab\/wp-json\/wp\/v2\/posts\/4440\/revisions"}],"predecessor-version":[{"id":4442,"href":"https:\/\/amphibian.hiroshima-u.ac.jp\/~oginolab\/wp-json\/wp\/v2\/posts\/4440\/revisions\/4442"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/amphibian.hiroshima-u.ac.jp\/~oginolab\/wp-json\/wp\/v2\/media\/3899"}],"wp:attachment":[{"href":"https:\/\/amphibian.hiroshima-u.ac.jp\/~oginolab\/wp-json\/wp\/v2\/media?parent=4440"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/amphibian.hiroshima-u.ac.jp\/~oginolab\/wp-json\/wp\/v2\/categories?post=4440"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/amphibian.hiroshima-u.ac.jp\/~oginolab\/wp-json\/wp\/v2\/tags?post=4440"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}