We are studying the molecular mechanisms for mesodermal and neural development in the body axis formation of vertebrates and for the regulation of stem cells and tissue regeneration. Our goal is to clarify “how a single fertilized egg gives rise to a well-organized body during development” and “how amphibians are capable of regenerating organs and tissues after injury”. The African clawed frog Xenopus laevis and X. tropicalis are ideal model system for studying vertebrate embryogenesis/regeneration and the etiology of human genetic diseases, as frog eggs are accessible to a variety of genetic modification methods and embryological manipulations. We are particularly interested in the roles of cell signaling mediated by growth factors and downstream transcription factors. Recently, we discovered the essential roles of Zbtb14 in the formation of dorsal-ventral and anterior-posterior axes (Takebayashi-Suzuki et al., 2018), the regulation of neural development by the autism-related Clk2 (Virgirinia et al., 2019), and the importance of JunB in the initiation of cell proliferation during regeneration (Nakamura et al., 2020).
Atsushi Suzuki served as a Guest Referee of the presentation gland prix for young students (2021.01.11) Four Poster Presentations at MBSJ2020 online (annual meeting of molecular biology society of Japan) (2020.12.02) Welcoming lunch party for a newly joined undergraduate student (2020.12.01) Lab picnic party to celebrate Awards and Review Article Publication, etc. (2020.11.01) Makoto Nakamura (D2) was selected as an Oral Presenter among two other Poster Presentations at online trial meeting 2020 (Japanese society of developmental biologists) (2020.09.24)
2020 welcoming lunch party for new lab members. We all enjoy research and education!
Regina Putri Virgirinia
In our laboratory, we have students from not only Hiroshima University but also other universities. We all enjoy science and education to contribute to the societies and aim at discovering novel molecular mechanisms regulating embryogenesis and regeneration. Throughout the year, we participate in a variety of research and educational activities including a joint project with high-school teachers. Please join us and enjoy together!